1st Faculty of Medicine Charles University 1st Faculty of Medicine Charles University Genes, Genetics & Genomics

April 6-7, 2017 G3


The G3 symposium will start in the main Lecture hall after the lecture ofDr. Bernd Zetsche (Broad Institute, USA), 2nd Programmable Nucleases (CRISPR/Cas9) Transgenesis Course 8.30-9.15. Audience of G3 is welcome to attend. Title "Development CRISPR-Cas9 & Cpf1 technology"

April 6, 2017 9.30 A.M. - 3 P.M. BIOCEV, Průmyslová 595, Vestec


Dr. Britta Will, britta.will@einstein.yu.edu

Albert Einstein College of Medicine, New York, USA

title: "Hematopoietic Stem Cell Aging and Leukemogenesis"

Areas of Research: Hematopoietic Stem Cells (HSC), Regulation of Stem Sell Fate, Myelodysplastic Syndrome and Acute Myeloid Leukemia, Mouse Models of Leukemogenesis, Testing of novel stem cell-directed therapeutics on primary human HSCs.

Dr. Meritxell Alberich Jorda,  meritxell.alberich-jorda@img.cas.cz

Institute of Molecular Genetics, Prague

title: "Searching for the good players: EVI2B controls granulocytic differentiation and progenitor functions"

Areas of Research: We investigate how C/EBPs regulate granulocytic production, whether they are mutated or deregulated during leukemogenesis, and how these alterations participate in the development of human acute myeloid leukemia (AML).

Dr. Annalisa di Ruscio:

Università del Piemonte Orientale, Novara, Italy

title:"ReDirecting DNA methylation"

Area of Research: to investigate the functional role of DNMT1-interacting RNAs in leukemogenesis and to pave the way for the development of the first gene-specific demethylating tool to apply in cancer and other diseases where aberrant DNA methylation plays a pivotal role.

Prof. Dr. Gerhard Behre

Leipzig University Hospital, Germany

Title: "Disturbance of the C/EBPalpha-miR-182 balance impairs granulocytic differentiation and promotes development of acute myeloid leukemia"

Areas of Research: The role of transcription factor C/EBPalpha and microRNAs in myeloid differentiation and acute myeloid leukemia.

April 7, 2017 9 A.M. - 2 P.M.  Dean's Office (Na bojišti 3, Praha)

Dr. Sheela Abraham: Sheela.Abraham@glasgow.ac.uk 

Paul O'Gorman Research Centre, Gartnavel General Hospital, Glasgow

title: Taking control of signal transduction networks in CML

Research Area: transcription factor targeting in Chronic Myeloid Leukaemia, roles of p53 and c-myc.

Dr. Martin Kortüm Kortuem_M@ukw.de

Universitätsklinikum Würzburg, Germany

title: “Targeted next gen sequencing in Multiple Myeloma”

Research Area: genetic background and mechanisms of drug resistance in hematologic malignancies, with an emphasis on plasma cell dyscrasias such as multiple myeloma.

Prof. Jaroslav Doležel dolezel@ueb.cas.cz

Institute of Experimental Botany (IEB), Olomouc

title: "Chromosome-centric approaches to plant genomics and gene cloning"

Research Area: hereditary information of plants, its organization and changes, which accompanied evolution of plants and origin of new species. With his team he developed new methods to facilitate the analysis of complex plant genomes and participates in several international consortia aiming at sequencing genomes of important plants.

Organizers: 1st Faculty of Medicine, Charles University & Institute of Haematology and Blood Transfusion (ÚHKT)