II. mezinárodní symposium o genové regulaci
u normálních a patologických stavů
The 2ND International Symposium on Gene Regulation in Health and Disease
„mechanisms of leukemogenesis and lymphomagenesis“
1. lékařská fakulta Univerzity Karlovy, Praha, Česká republika
Čtvrtek 9. září 2010, 8:30-16:30 h
Zasedací místnost v přízemí děkanátu 1. lékařské fakulty UK
Na Bojišti 3, 121 08 Praha 2, Česká republika
First Medical Faculty, Charles University, Prague, Czech Republic
Thursday 9th September, 2010, 8:30 am-4:30 pm
Conference Room, Ground floor of the Dean’s Office Building
First Medical Faculty, Charles University
Na Bojišti 3, 121 08 Prague 2, Czech Republic
Rozvrh přednášek / presentation Schedule
Dopolední sekce / Morning Session (Moderátor / Chair: T. Stopka)
08:30 – 08:45
Úvod Děkana fakulty/ Introduction by Dean of the faculty
08:45 - 09:00
Úvodní poznámky / Opening remarks : Stem cells, differentiation and human disease.
Emanuel Nečas, Charles University in Prague
09:00 - 09:30
Acute myeloid leukemia: a moving target (I)
Stefan Bohlander, University of Munich
09:45 -10:15
Gene Regulatory Networks that Regulate Macrophage Development
Peter Laslo, University of Leeds
10:30 – 10:45 Přestávka / Coffee break
10:45 - 11:15
The oncogenic miR-17-92 microRNA cluster is inhibited by EGR2 during macrophage differentiation via JARID1b-mediated Histone 3 lysine 4 demethylation.
Vit Pospíšil, Charles University in Prague
11:30 - 12:00
WNT/PCP signaling in chronic lymphocytic leukemia
Vitězslav Bryja, Masaryk University in Brno
Odpolední sekce / Afternoon session (Moderátor / Chair: T. Stopka)
Clinical Applications of Basic Research
14:15 - 14:30
Úvodní poznámky / Opening remarks
Biological therapy in hematologic malignancies.
Marek Trněný, Charles University in Prague
14:30 -14:50
Acute myeloid leukemia: a moving target (II)
Stefan Bohlander, University of Munich
15:00 - 15:20
Pro-tumor functions of macrophages.
Peter Laslo, University of Leeds
15:30 - 15:50
Mouse model of human mantle cell lymphoma: gene expression signatures of the lymphoma subpopulations and implications for therapeutic approaches.
Pavel Klener, Charles University in Prague
16:00 -16:20
Dysregulation of chromatin structure near MYB occupancy upstream of the
miR-155 host gene in chronic lymphocytic leukemia.
Tomáš Stopka, Charles University in Prague
