You can read a Medical Tribune symposium report (in Czech) here.
DAY 1 - Thursday, 10 May, 2012
VENUE: Seminar Room 1.26, U nemocnice 4, Prague 2
9.00 am - 9.15 am
Historical Mission of the Host Institution - Opening Presentation
Emanuel NEČAS, Pathological Physiology, First Faculty of Medicine, Charles University in Prague, Czech Republic
Gene Regulation in Tumour Cells (Chair: J. Zavadil)
9.15 am - 10.00 am
Pathological Interference of Myeloid Differentiation by the BCR-ABL Oncogene
Peter LASLO, Leeds Institute of Molecular Medicine, University of Leeds, United Kingdom
10.00 am - 10.30 am
MicroRNA-650 Expression Is Influenced By Immunoglobulin Gene Rearrangement and Affects the Biology of Chronic Lymphocytic Leukemia (CLL)
Marek MRÁZ, Faculty of Medicine & Central European Institute of Technology, Masaryk University, Brno, Czech Republic and University of California-San Diego, La Jolla, CA, USA
10.30 am - 10.45am Coffee break
10.45 am - 11.15 am
Extracellular MicroRNAs in Patients with Lymphomas of the Central Nervous System
Vít POSPÍŠIL, Pathological Physiology, First Faculty of Medicine, Charles University in Prague, Czech Republic
11.15 am - 11.45 am
Importance of Regulation of PU.1 Expression for Aggressiveness of Hematological Malignancies
Tomáš STOPKA, Pathological Physiology, First Faculty of Medicine, Charles University in Prague, Czech Republic
11.45 am - 12.00 pm
Presentation Life Technologies
12.00 pm - 12.15 pm
Presentation KRD: Zbyněk HALBHUBER
12.15 pm - 2.00 pm LUNCH BREAK
Cell Biology and Pathophysiology (Chair: T. Stopka)
2.00 pm - 2.30 pm
Tyrosine Phosphorylation within CAS SH3 Domain Regulates Cell Migration and Invasiveness
Jan BRÁBEK, Department of Cell Biology, Charles University, Prague, Czech Republic
2.30 pm - 3.00 pm
Roscovitine Sensitizes Leukemia/Lymphoma Cells to TRAIL-Induced Apoptosis and Enhances Cell Mediated Cytotoxicity
Jan MOLÍNSKÝ, Pathological Physiology, First Faculty of Medicine, Charles University in Prague, Czech Republic
3.00 pm - 3.30 pm
Beauty Hidden In Lipids - Proteomic Analysis of Membrane Proteins Based On Their Transmembrane Peptides
Jiri PETRÁK,Pathological Physiology, First Faculty of Medicine, Charles University in Prague, Czech Republic
3.30 pm - 3.45 pm Coffee break
3.45 pm - 4.15 pm
Elucidating the Role of Alpha-Synuclein Promoter Binding In Transcriptional Dysregulation
Fran BOROVEČKI, Zagreb Medical School, University Hospital Center, University of Zagreb, Croatia
4.15 pm - 4.45 pm
Pathogenetic Common Molecular Mechanism in Homocystinuria: Misfolding Of Cystathionine Beta-Synthase Mutants and Effect of Chaperones
Viktor KOŽICH, Institute of Inherited Metabolic Diseases, First Faculty of Medicine, Charles University in Prague, Czech Republic
DAY 2 - Friday 11 May, 2012
VENUE: Seminar Room 1.26, U nemocnice 4, Prague 2
Transcription and Cell Fate (Chair: P. Laslo)
9.00 am - 9.45 am
Constructing and Deconstructing Spinal Motor Neurons
Hynek WICHTERLE, Columbia University Medical Center, New York, USA
9.45 am - 10.15 am
Post-Transcriptional Regulations during the Oocyte-To-Zygote Transition
Petr SVOBODA, Institute of Molecular Genetics AS CR, Prague, Czech Republic
10.15 am - 10.30am Coffee break
10.30 am - 11.00 am
Wnt Signaling In Adult Stem Cells – An Insight from the Gut
Vladimír KOŘÍNEK, Institute of Molecular Genetics AS CR, Prague, Czech Republic
11.00 am - 11.30 am
Transcriptional Pulsing and the Control of Cellular Differentiation
Christian LANCTÔT, First Faculty of Medicine, Charles University in Prague, Czech Republic
11.30 am - 12.00 pm
Nuclear PIP2 and Myosin I: New Important Players in DNA Transcription
Pavel HOZÁK, Institute of Molecular Genetics AS CR, Prague, Czech Republic
12.00 pm - 12.15 pm
What is GS Junior used for?
Petr ŽÁK, Roche diagnostics
12.15 pm - 2.00 pm LUNCH BREAK
Genetics and Genome Integrity (Chair: H. Wichterle)
2.00 pm - 2.45 pm
Acute Myeloid Leukemia: Unraveling the Genetics and Exploring Critical Pathways
Stefan BOHLANDER, Philipps University Marburg and University of Munich, Germany
2.45 pm - 3.15 pm
Rare Genetic Variants in Mendelian and Complex Diseases
Stanislav KMOCH, First Faculty of Medicine, Charles University in Prague, Czech Republic
3.15 pm - 3.45 pm
Molecular Fingerprints of Human Urothelial Carcinogenesis Revealed by Integrated Genomic Profiling
Jiří ZAVADIL, New York University Langone Medical Center, New York, NY, USA
3.45 pm - 4.00 pm Coffee break
4.00 pm - 4.30 pm
Alternative Splicing of BRCA1 - Desired Tool for DNA Repair Regulation or “Messy Garbage” of Splicing Events?
Zdeněk KLEIBL, First Medical Faculty, Charles University, Prague, Czech Republic
4.30 pm - 5.00 pm
Cd36-Deficient Congenic Strains Show Improved Glucose Tolerance and Distinct Shifts in Transcriptomic and Metabolic Profiles
Ondřej ŠEDA, First Faculty of Medicine, Charles University in Prague and Centre hospitalier de l'Université de Montréal (CRCHUM) – Technôpole Angus, Montreal, Quebec, Canada
5.00 pm Concluding remarks
Tomáš STOPKA, Charles University in Prague, Czech Republic
